Douglas Stuart Portman, Ph.D.
Contact
Connect with Douglas Stuart Portman, Ph.D.
About Me
Faculty Appointments
Professor - Department of Biomedical Genetics (SMD)
Donald M. Foster, MD Professorship in Biomedical Genetics - Department of Biomedical Genetics (SMD)
Professor - Department of Biology RC (RC) - Joint
Professor - Department of Neuroscience (SMD) - Joint
Credentials
Education
PhD | Univ of Pennsylvania. Molecular Biology and Genetics. 1995
BA with Honors, | Univ of Pennsylvania. Biochemistry. 1988
Research
Though the existence of two sexes is a fundamental characteristic of nearly all animal species, the way biological sex brings about sex differences in the brain and behavior is poorly understood. Moreover, susceptibility to a host...
Though the existence of two sexes is a fundamental characteristic of nearly all animal species, the way biological sex brings about sex differences in the brain and behavior is poorly understood. Moreover, susceptibility to a host of human neurological and mental health disorders is strongly influenced by gender, but in most cases the biological bases for these differences remain opaque. Our research uses a simple, experimentally tractable model system--the small soil nematode C. elegans--to shed light on the genetic underpinnings of sex differences in neural development, behavior, and disease susceptibility.
For more information, please visit the lab website at: http://wormweb.urmc.rochester.edu/
Publications
Journal Articles
Luo J, Bainbridge C, Miller RM, Barrios A, Portman DS
Current biology : CB.. 2024 March 7 Epub 03/07/2024.
Portman DS, DÃaz-Balzac CA
Current biology : CB.. 2023 October 933 (19):R1016-R1018. Epub 1900 01 01.
Luo J, Barrios A, Portman DS
bioRxiv : the preprint server for biology.. 2023 April 8 Epub 04/08/2023.
Burkhardt RN, Artyukhin AB, Aprison EZ, Curtis BJ, Fox BW, Ludewig AH, Palomino DF, Luo J, Chaturbedi A, Panda O, Wrobel CJJ, Baumann V, Portman DS, Lee SS, Ruvinsky I, Schroeder FC
Nature communications.. 2023 January 1914 (1):320. Epub 01/19/2023.
Pechuk V, Goldman G, Salzberg Y, Chaubey AH, Bola RA, Hoffman JR, Endreson ML, Miller RM, Reger NJ, Portman DS, Ferkey DM, Schneidman E, Oren-Suissa M
Current biology : CB.. 2022 September 1 Epub 09/01/2022.
Luo J, Portman DS
Current biology : CB.. 2021 August 19 Epub 08/19/2021.
Portman DS
Journal of neurogenetics.. 2020 November 4 :1-6. Epub 11/04/2020.
Lawson HN, Wexler LR, Wnuk HK, Portman DS
Current biology : CB.. 2020 July 19 Epub 07/19/2020.
Wexler LR, Miller RM, Portman DS
Current biology : CB.. 2020 May 28 Epub 05/28/2020.
Alcedo J, Jin Y, Portman DS, Prahlad V, Raizen D, Rapti G, Xu XZS, Zhang Y, Wu CF
Journal of neurogenetics.. 2020 34 (3-4):223-224. Epub 1900 01 01.
Lawson H, Vuong E, Miller RM, Kiontke K, Fitch DH, Portman DS
eLife.. 2019 July 28 Epub 07/02/2019.
Portman DS
Nature.. 2019 July 571 (7763):40-42. Epub 1900 01 01.
Kiontke KC, Herrera RA, Vuong E, Luo J, Schwarz EM, Fitch DHA, Portman DS
Developmental cell.. 2019 May 2049 (4):542-555.e9. Epub 04/04/2019.
Pereira L, Aeschimann F, Wang C, Lawson H, Serrano-Saiz E, Portman DS, Großhans H, Hobert O
eLife.. 2019 January 18 Epub 01/01/2019.
Fagan KA, Luo J, Lagoy RC, Schroeder FC, Albrecht DR, Portman DS
Current biology : CB.. 2018 March 1928 (6):902-914.e5. Epub 03/08/2018.
Barr MM, GarcÃa LR, Portman DS
Genetics.. 2018 March 208 (3):909-935. Epub 1900 01 01.
Portman DS
Journal of neuroscience research.. 2017 January 295 (1-2):527-538. Epub 1900 01 01.
GarcÃa LR, Portman DS
Current opinion in neurobiology.. 2016 June 38 :46-52. Epub 03/03/2016.
Portman DS
Nature.. 2016 May 12533 (7602):188-9. Epub 05/04/2016.
Portman DS, Biteau B
Cell stem cell.. 2016 April 718 (4):429-30. Epub 1900 01 01.
Ryan DA, Miller RM, Lee K, Neal SJ, Fagan KA, Sengupta P, Portman DS
Current biology : CB.. 2014 November 324 (21):2509-17. Epub 10/16/2014.
Fagan KA, Portman DS
Seminars in cell & developmental biology.. 2014 September 33 :3-9. Epub 06/14/2014.
Mowrey WR, Bennett JR, Portman DS
The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2014 January 2934 (5):1579-91. Epub 1900 01 01.
Mowrey WR, Portman DS
Biology of sex differences.. 2012 March 213 :8. Epub 03/21/2012.
Miller RM, Portman DS
The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2011 September 1431 (37):13281-91. Epub 1900 01 01.
Siehr MS, Koo PK, Sherlekar AL, Bian X, Bunkers MR, Miller RM, Portman DS, Lints R
PloS one.. 2011 6 (11):e26811. Epub 11/01/2011.
Hurd DD, Miller RM, Núñez L, Portman DS
Genetics.. 2010 July 185 (3):883-96. Epub 04/26/2010.
Miller RM, Portman DS
Disease models & mechanisms.. 2010 3 (7-8):441-50. Epub 03/11/2010.
Mason DA, Rabinowitz JS, Portman DS
Development.. 2008 August 135 (14):2373-82. Epub 06/11/2008.
Lee K, Portman DS
Current biology : CB.. 2007 November 617 (21):1858-63. Epub 10/25/2007.
Portman DS
Advances in genetics.. 2007 59 :1-37. Epub 1900 01 01.
Portman DS
WormBook : the online review of C. elegans biology.. 2006 January 20 :1-11. Epub 01/20/2006.
Portman DS, Bohmann D
Molecular cell.. 2004 June 1814 (6):693-4. Epub 1900 01 01.
Portman DS, Emmons SW
Developmental biology.. 2004 June 15270 (2):499-512. Epub 1900 01 01.
Portman DS, Emmons SW
Development.. 2000 December 127 (24):5415-26. Epub 1900 01 01.
Portman DS, O'Connor JP, Dreyfuss G
RNA.. 1997 May 3 (5):527-37. Epub 1900 01 01.
Kamma H, Portman DS, Dreyfuss G
Experimental cell research.. 1995 November 221 (1):187-96. Epub 1900 01 01.
Portman DS, Dreyfuss G
The EMBO journal.. 1994 January 113 (1):213-21. Epub 1900 01 01.
Görlach M, Burd CG, Portman DS, Dreyfuss G
Molecular biology reports.. 1993 August 18 (2):73-8. Epub 1900 01 01.